MagicSportsBreakdown|NFL Week 10 Matchups

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NFL Week 10 matchups, all 14 games. Highest total: San Francisco 49ers at Dallas Cowboys, 56.5. Biggest favorite: Jacksonville Jaguars -10.5. Best RB matchup on the slate: Kansas City Chiefs, ARBY 1st. Every game below has a free preview; the Thursday Night Football, Sunday Night Football and Monday Night Football games open in full with a free StatRankings account.

Thursday Night Football Matchup

WAS +1.5 (+106) · NYG -1.5 (-106)O/U 42.5 (T-8th)Over +106 / Under -106ARBY RB Matchup Rank20th24th
NYG -1.5-106O/U 42.5o+106 u-106ARBY RB Rank20th24th

Who's favored? New York Giants by 1.5. Best RB matchup: Washington Commanders, ARBY 20th.

Sunday

NE +2.5 (+115) · DET -2.5 (-115)O/U 50.5 (T-2nd)Over -113 / Under +113ARBY RB Matchup Rank14th6th
DET -2.5-115O/U 50.5o-113 u+113ARBY RB Rank14th6th

Who's favored? Detroit Lions by 2.5. Best RB matchup: Detroit Lions, ARBY 6th.

BUF -7.5 (+102) · NYJ +7.5 (-102)O/U 50.5 (T-2nd)Over +102 / Under -102ARBY RB Matchup Rank3rd18th
BUF -7.5+102O/U 50.5o+102 u-102ARBY RB Rank3rd18th

Who's favored? Buffalo Bills by 7.5. Best RB matchup: Buffalo Bills, ARBY 3rd.

CAR +1.5 (-102) · NO -1.5 (+102)O/U 48.5 (T-4th)Over +104 / Under -104ARBY RB Matchup Rank8th17th
NO -1.5+102O/U 48.5o+104 u-104ARBY RB Rank8th17th

Who's favored? New Orleans Saints by 1.5. Best RB matchup: Carolina Panthers, ARBY 8th.

HOU -4.5 (-106) · CLE +4.5 (+106)O/U 40.5 (T-11th)Over +113 / Under -113ARBY RB Matchup Rank23rd19th
HOU -4.5-106O/U 40.5o+113 u-113ARBY RB Rank23rd19th

Who's favored? Houston Texans by 4.5. Best RB matchup: Cleveland Browns, ARBY 19th.

JAX -10.5 (+102) · TEN +10.5 (-102)O/U 46.5 (6th)Over -102 / Under +102ARBY RB Matchup Rank9th15th
JAX -10.5+102O/U 46.5o-102 u+102ARBY RB Rank9th15th

Who's favored? Jacksonville Jaguars by 10.5. Best RB matchup: Jacksonville Jaguars, ARBY 9th.

KC -3.5 (+108) · ATL +3.5 (-108)O/U 44.5 (7th)Over -108 / Under +108ARBY RB Matchup Rank1st12th
KC -3.5+108O/U 44.5o-108 u+108ARBY RB Rank1st12th

Who's favored? Kansas City Chiefs by 3.5. Best RB matchup: Kansas City Chiefs, ARBY 1st.

MIA +2.5 (-102) · IND -2.5 (+102)O/U 40.5 (T-11th)Over -104 / Under +104ARBY RB Matchup Rank10th11th
IND -2.5+102O/U 40.5o-104 u+104ARBY RB Rank10th11th

Who's favored? Indianapolis Colts by 2.5. Best RB matchup: Miami Dolphins, ARBY 10th.

MIN +4.5 (+111) · GB -4.5 (-111)O/U 42.5 (T-8th)Over -102 / Under +102ARBY RB Matchup Rank21st27th
GB -4.5-111O/U 42.5o-102 u+102ARBY RB Rank21st27th

Who's favored? Green Bay Packers by 4.5. Best RB matchup: Minnesota Vikings, ARBY 21st.

LAR -9.5 (-106) · ARI +9.5 (+106)O/U 40.5 (T-11th)Over +120 / Under -120ARBY RB Matchup Rank4th25th
LAR -9.5-106O/U 40.5o+120 u-120ARBY RB Rank4th25th

Who's favored? Los Angeles Rams by 9.5. Best RB matchup: Los Angeles Rams, ARBY 4th.

SEA -3.5 (+104) · LV +3.5 (-104)O/U 42.5 (T-8th)Over -113 / Under +113ARBY RB Matchup Rank13th28th
SEA -3.5+104O/U 42.5o-113 u+113ARBY RB Rank13th28th

Who's favored? Seattle Seahawks by 3.5. Best RB matchup: Seattle Seahawks, ARBY 13th.

SF -3.5 (-106) · DAL +3.5 (+106)O/U 56.5 (1st)Over +111 / Under -111ARBY RB Matchup Rank2nd16th
SF -3.5-106O/U 56.5o+111 u-111ARBY RB Rank2nd16th

Who's favored? San Francisco 49ers by 3.5. Best RB matchup: San Francisco 49ers, ARBY 2nd.

PIT +3.5 (+102) · CIN -3.5 (-102)O/U 48.5 (T-4th)Over +102 / Under -102ARBY RB Matchup Rank5th22nd
CIN -3.5-102O/U 48.5o+102 u-102ARBY RB Rank5th22nd

Sunday Night Football matchup: Who's favored? Cincinnati Bengals by 3.5. Best RB matchup: Pittsburgh Steelers, ARBY 5th.

Monday Night Football Matchup

LAC +5.5 (-102) · BAL -5.5 (+102)O/U 38.5 (14th)Over -100 / Under -100ARBY RB Matchup Rank26th7th
BAL -5.5+102O/U 38.5o-100 u-100ARBY RB Rank26th7th

Who's favored? Baltimore Ravens by 5.5. Best RB matchup: Baltimore Ravens, ARBY 7th.

Game-by-Game Week 10 Matchups. WR/CB matchup data with Man/Zone & Shell Coverage splits. Pace & play-calling (PROE+). Explosive play data. Adjusted Run Blocking Yards (ARBY) RB Matchup Grades. 1st-read target share, RZ & GL usage, on/off splits, & advanced fantasy metrics.

Stats used in this tool

Every number here is pulled from a live statrankings leaderboard. Open any stat for the definition, the full 32-team or player board, and week-by-week splits.

Ranks: defensive ranks read from the offense's side, #1 is the most generous matchup. Green 1-12, yellow 13-22, red 23-32. Source: statrankings.com · Data as of 2026-11-10